近日,课题组成员赵鹏飞、郑明彬等成功制备了一种纳米氧载体,该载体具有优良的载氧能力和ATP响应的药物释放。通过向肿瘤细胞提供充足氧气干预细胞内线粒体代谢,该载体实现了增强的化疗和ROS毒性协同的肿瘤细胞杀伤效果。相关成果已发表于Advanced Healthcare Materials(影响因子5.797),题目为“Oxygen Nanocarrier for Combined Cancer Therapy: Oxygen-Boosted ATP-Responsive Chemotherapy with Amplified ROS Lethality”, DOI: 10.1002/adhm.201600121. Authors: Pengfei Zhao, Mingbin Zheng*, Zhenyu Luo, Xiujun Fan, Zonghai Sheng, Ping Gong, Ze Chen, Baozhen Zhang, Dapeng Ni, Yifan Ma*, Lintao Cai*.