2014.06.19. 课题组成员方胜涛、吴蕾等首次利用多肽纳米胶束系统性传递ZEB1 siRNA用于肺癌治疗,结果显示该纳米系统能够抗肿瘤转移和增强肿瘤细胞对化疗药物的敏感性,为癌症的治疗提供了新的思路和策略。文章接收发表于Nanoscale(IF=6.233),题目为:Polypeptide cationic micelles mediated knockdown of ZEB1 inhibits metastasis and sensitizes chemotherapeutic drug for cancer therapy.